Design and synthesis of novel CYP24A1 inhibitors

CYP24A1 (25-hydroxyvitamin D-24-hydroxylase) is a useful enzyme target for a range of medical conditions including cancer, cardiovascular and autoimmune disease, which show elevated CYP24A1 levels and corresponding reduction of calcitriol (the biologically active form of vitamin D). Calcitriol has a...

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Bibliographic Details
Main Author: Taban, Ismail
Published: Cardiff University 2017
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725689