Development of a targeted next-generation sequencing gene panel to investigate recurrent mutations in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a mono-clonal B-cell malignancy characterised by heterogeneous clinical course and response to treatment. Recent studies with whole genome or whole exome sequencing have identified novel recurrent genomic lesions, and associated them with adverse clinical outco...

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Bibliographic Details
Main Author: Karim, S. Q.
Other Authors: Lin, Ke ; Pettitt, A. R. ; Johnson, Gillian
Published: University of Liverpool 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.724463