The role of insulin receptor substrate 2 in beta cell function

Insulin receptor substrate (Irs) 2 plays complex roles in the regulation of glucose homeostasis, energy balance and CNS development. To address the tissue-specific role of Irs2 signalling events, conditional Irs2-deficient mice were generated. IrsHoxAox mice were crossed with mice expressing Cre rec...

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Bibliographic Details
Main Author: Heffron, Helen
Published: University College London (University of London) 2007
Subjects:
612
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719035