In vitro expansion of donor-derived CMV-specific T lymphocytes for adoptive cellular therapy : optimisation of antigen presentation by dendritic cells, characterisation of the culture output, and adaptation of culture conditions to CMV-naïve donors
Cytomegalovirus infection adversely affects the survival of haemopoietic stem cell transplant recipients, despite antiviral chemotherapy. As an alternative treatment, adoptive cellular therapy can transfer specific immunity from donor to recipient, avoiding drug side effects. A range of methods for...
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University College London (University of London)
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719015 |