Unfolding of the von Willebrand factor A2 domain
von Willebrand factor (VWF) is a multidomain glycoprotein that has well-established functions in haemostasis and thrombosis. The lack of a constraining disulphide bond results in unfolding of its VWF A2 domain under rheological forces in the vasculature. This unfolding of the VWF A2 domain is an imp...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
Imperial College London
2017
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718445 |