Remodelling of the cardiac caveolar domain in heart failure and its putative influence on beta adrenergic signalling

Over 500,000 people in the UK have heart failure (HF). After an initial insult to the heart, sympathetic drive increases which leads to detrimental remodelling of cardiac β-adrenergic receptors (βAR) and further cardiac dysfunction. The main βAR expressed in the heart are the β1AR and β2AR. In heart...

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Bibliographic Details
Main Author: Norman, Ruth Anne Astley
Other Authors: Calaghan, Sarah C. ; White, Ed
Published: University of Leeds 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713211