Identification of genes involved in reprogramming-induced senescence

Senescence is a state of irreversible growth arrest first described in human fibroblasts when they undergo serial passage in vitro. Senescence can also occur in response to different stresses, such as replicative exhaustion, DNA damage or overexpression of oncogenes. The growth arrest associated wit...

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Bibliographic Details
Main Author: Beolchi, Patrizia
Other Authors: Gil, Jesus
Published: Imperial College London 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712827