Biophysical and functional studies of potential G-quadruplex motifs from the proximal GATA4 gene promoter

GATA4 is well known as a cardiac transcription factor and recently has also been implicated in several cancers. Therefore, a fundamental understanding of its gene regulation is currently of high interest. It has been suggested that guanine-rich motifs found in gene promoters could potentially adopt...

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Bibliographic Details
Main Author: Klejevskaja, Beata
Other Authors: Vilar, Ramon ; Ying, Liming ; Schneider, Michael D.
Published: Imperial College London 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712824