Design and synthesis of novel compounds to inhibit CSF-1R & evaluation of novel substrates and reactivities in NHC catalysis
Chapter I describes work undertaken on a Medicinal Chemistry project studying the small molecule inhibition of the protein CSF-1R. Initial computational work, using the Cresset software package, involved modeling the key steric and electrostatic properties of compounds known to bind to the active si...
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Imperial College London
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712821 |