Structural and functional studies of K2P channels

Two-pore domain potassium channels (K2Ps) are a family of dimeric potassium channels responsible for regulation of cellular excitability. In 2012, crystal structures of TREK-2 were solved revealing this channel in two different conformational states. In the down state, transmembrane helices M2, 3 an...

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Bibliographic Details
Main Author: Mackenzie, Alexandra
Other Authors: Tucker, Stephen ; Carpenter, Liz
Published: University of Oxford 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712476