Novel approaches for targeting BRCA2-deficient tumour cells

Defects in homologous recombination (HR) repair are associated with significant mortality and improved therapies for HR-deficient tumours are therefore urgently needed. This work aimed to address this unmet need and utilised pharmacological approaches to investigate several methods for the targeting...

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Bibliographic Details
Main Author: Tacconi, Eliana Maria Cristina
Other Authors: Tarsounas, Magdalena ; Ryan, Anderson
Published: University of Oxford 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712419