The application of click reactions in the synthesis of modified oligonucleotides
'Click' chemistry has been widely applied in nucleic acid studies, the most common reactions being the copper-catalysed and strain promoted alkyne-azide cycloadditions (CuAAC and SPAAC respectively). This thesis describes the use of these complementary reactions in the synthesis of modifie...
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University of Oxford
2015
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712404 |