The application of click reactions in the synthesis of modified oligonucleotides

'Click' chemistry has been widely applied in nucleic acid studies, the most common reactions being the copper-catalysed and strain promoted alkyne-azide cycloadditions (CuAAC and SPAAC respectively). This thesis describes the use of these complementary reactions in the synthesis of modifie...

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Bibliographic Details
Main Author: Qiu, Jieqiong
Other Authors: Brown, Tom
Published: University of Oxford 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712404