Engineering cholera toxin for the targeted delivery of oligonucleotides
Half of the 20 best-selling prescription drugs of 2014 were large biologic therapeutics, however to date there have only been two licensed non-aptamer oligonucleotide drugs. Oligonucleotides have proven highly successful at modification of gene expression in the laboratory, but the lack of a robust...
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University of Leeds
2016
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707042 |