The role and regulation of AKT in CD40-mediated survival and proliferation of CLL cells

Chronic lymphocytic leukaemia (CLL) is a proliferative disease in which malignant B lymphocytes gradually accumulate in the peripheral blood, lymph nodes and bone marrow. It is the most common leukaemia in adults and currently incurable. Novel therapeutic strategies are thus required. The serine/thr...

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Bibliographic Details
Main Author: Chapman, E. A.
Published: University of Liverpool 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706807