Romidepsin : molecular analysis of the in vitro effects and its potential for combination therapy in MDS/AML
Myelodysplatic syndrome (MDS) patients have poor tolerability of standard chemotherapies and an unmet need for therapeutic approaches. Epigenetic silencing of genes can occur through many mechanisms including DNA hypermethylation or the recruitment of histone deacetylases (HDACs), with these changes...
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Queen's University Belfast
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705889 |