Investigating inhibitors of the IgE:high affinity receptor protein-protein interaction

The protein-protein interaction (PPI) between immunoglobulin E (IgE) and its high affinity receptor (FcεRI) is an important part of the allergic response. Inhibition of the IgE:FcεRI interaction is a key strategy for the development of allergy treatments. This PPI has been validated as a therapeutic...

Full description

Bibliographic Details
Main Author: Smith, Lucy
Other Authors: Spivey, Alan ; Leatherbarrow, Robin
Published: Imperial College London 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705761