A multiscale simulation approach to study the membrane-spanning regions of integral membrane proteins

Despite the progress in structural biology over the last decades, it is still challenging to determine the structure of the transmembrane domains (TMDs) of integral membrane proteins. The work of this thesis has focused on two groups of integral membrane proteins: Toll-like receptors (TLRs) and poly...

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Bibliographic Details
Main Author: Kargas, Vasileios
Other Authors: Ford, Robert ; Baldock, Clair
Published: University of Manchester 2017
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.703026