Cross-talk between the primary tumour and brain metastases enhances the efficacy of immune checkpoint inhibition

Melanoma brain metastases (MBrM) are devastating, occurring in up to 60% of melanoma patients and are increasing in incidence as systemic treatments improve. MBrM are notoriously difficult to treat and patients suffer from extremely poor survival rates, resulting in these patients being excluded fro...

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Bibliographic Details
Main Author: Taggart, David John
Other Authors: Lorger, Mihaela ; Melcher, Alan ; Ilett, Elizabeth
Published: University of Leeds 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702623