(+)-Laccarin : a design template for novel heterocyclic scaffolds
Investigations into the biological activity of alkaloid (+ )-laccarin have been performed. This report is the first to identify the selectivity of this natural product for phosphodiesterase 5 and an X-ray crystal structure has been acquired revealing the key binding interactions of the compound in t...
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University of Bristol
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702453 |