Phenotypic consequences of β-defensin copy number variation in humans

Beta defensins (DEFB) at the 8p23.1 genomic location are multifunctional secreted short peptides that have antibacterial and antiviral action in many species and possess immune cell signal activity, constituting a link between innate and adaptive immunity. In humans, the β-defensin region is known t...

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Bibliographic Details
Main Author: Abujaber, Razan
Other Authors: Hollox, Ed
Published: University of Leicester 2016
Subjects:
575
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700912