Second messenger modulation of the human ether a go-go related gene (HERG) potassium channel
HERG (human ether-a-go-go related gene) encodes the major pore-funding subunit of IKr, a current which is vital for normal repolarisation of the cardiac action potential. Attenuation of IKr can lead to long QT syndrome, which can predispose individuals to arrhythmias and sudden cardiac death. Given...
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University of Leicester
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697308 |