Approaches towards the synthesis of gem-difluorinated monosaccharide analogues

This thesis describes the synthesis of gem-difluorinated cyclic molecules using building block approaches based mainly on ring-closing metathesis (RCM) using commercially available ruthenium catalysts such as Grubbs' catalyst. In the first instance, 1-bromo-1,1-difluoroprop-2-ene was used to sy...

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Bibliographic Details
Main Author: Pintat, Stéphane
Published: University of Leicester 2003
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697250