A study of cellular polyamine uptake and cytotoxicity

The synthesis and study of a series of methylated polyamine-fluorophore conjugates is described in this thesis. The conjugates are related by the degree of N-methylation at the N1 and N8 positions of the spermidine backbone, to which is also attached the fluorescent group (MANT) via a short linker a...

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Bibliographic Details
Main Author: Martin, Benjamin
Published: University of Leicester 2002
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697097