Detection of DNA damage caused by N-nitrosoindoles

To evaluate the genotoxicity of N-nitrosoindoles, three model compounds, 1-nitrosoindole-3-acetonitrile (NIAN), 1-nitrosoindole-3-acetamide and l-nitrosoindole-3-acetic acid methyl ester, were reacted with isolated purine nucleotides at physiological pH. The profile of reaction products was identica...

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Bibliographic Details
Main Author: Lucas, Lynda T.
Published: University of Leicester 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697012