Studies of the molecular basis of selectivity and gating in the inward rectifier potassium channel Kir2.1

1. The molecular basis of selectivity and gating were investigated in wild-type and mutant forms of the inward rectifier K+ channel Kir2.1 (IRK1). 2. Kir2.1 channels show characteristic time-dependent gating kinetics due to a reversible voltage-dependent channel block by cytoplasmic polyamines. Muta...

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Bibliographic Details
Main Author: Abrams, Christopher John
Published: University of Leicester 2000
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696787