Mycaminose metabolism and control of tylosin synthesis in Streptomyces fradiae
Production of the macrolide antibiotic, tylosin, occurs by a combination of polyketide synthesis and deoxyhexose sugar metabolism in S. fradiae. Polyketide synthesis was stimulated by glycosylated tylosin-precursors, and by tylosin itself, in an S. fradiae strain disrupted in the glycosyltransferase...
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University of Leicester
2000
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696763 |