Functional consequences of inositol 1,4,5-trisphosphate receptor overexpression on the phosphoinositide signalling cascade

The ubiquitously expressed inositol 1,4,5-trisphosphate receptor (InsP3R) is a crucial component in the process of signal transduction, encoding an extracellular stimulus into an intracellular Ca2+ signal. In this study, mouse L-fibroblast cells, transfected with either type 1 (InsP3R) cDNA (L15) or...

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Bibliographic Details
Main Author: Davis, Richard Jon
Published: University of Leicester 1999
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696603