Nociceptin/orphanin FQ system and animal models of sepsis

The nociceptin receptor (NOP) and its ligand nociceptin/orphanin FQ (N/OFQ) have been shown to exert a modulatory effect on immune cells during sepsis. We evaluated the suitability of three different experimental animal models for studying changes in the nociceptin system; lipopolysaccharide (LPS)-i...

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Bibliographic Details
Main Author: Thomas, Róisín Clare
Other Authors: Thompson, Jonathan ; Lambert, David
Published: University of Leicester 2016
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696142