Transcriptome-profiling in porcine arteries to identify shear-responsive regulators of endothelial apoptosis
Atherosclerosis develops predominantly at regions of the arterial tree exposed to disturbed blood flow, which generates low, oscillatory shear stress (WSS) at the lumen. Of note, endothelial cells (EC) at lesion-prone regions are characterised by an increased rate of apoptosis, thus providing a pote...
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Imperial College London
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695492 |