The role of the co-chaperone p23 in androgen signalling and prostate cancer

The binding of ligand by cytoplasmic Androgen Receptor (AR) is a critical step in androgen signalling. In the cytoplasm, unliganded AR requires the recruitment and activity of several factors and chaperones that stabilise the receptor preventing its degradation and maintaining it in a ligand-binding...

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Bibliographic Details
Main Author: Querol i Cano, Laia
Other Authors: Lavery, Derek
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693903