Design and synthesis of N-Myristoyltransferase inhibitors : a promising treatment for malaria

Diseases caused by parasitic infections such as malaria represent a huge global health burden, and new therapies are in great demand. N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme important for multiple processes in vivo, and represents an attractive drug target to combat Plasmodium...

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Bibliographic Details
Main Author: Rackham, Mark
Other Authors: Leatherbarrow, Robin
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693897