Peptidomimetic approach to the inhibition of N-myristoyltransferase, a promising parasitic drug target

N-myristoyltransferase (NMT), a ubiquitous enzyme, found in a number of organisms including fungi, parasites and humans, catalyses the irreversible transfer of a C-14 chain (myristic acid) to the N-terminal glycine of specific target proteins, a process known as N-myristoylation. NMT has been report...

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Bibliographic Details
Main Author: Olaleye, Tayo
Other Authors: Tate, Ed
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693873

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