Peptidomimetic approach to the inhibition of N-myristoyltransferase, a promising parasitic drug target
N-myristoyltransferase (NMT), a ubiquitous enzyme, found in a number of organisms including fungi, parasites and humans, catalyses the irreversible transfer of a C-14 chain (myristic acid) to the N-terminal glycine of specific target proteins, a process known as N-myristoylation. NMT has been report...
Main Author: | Olaleye, Tayo |
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Other Authors: | Tate, Ed |
Published: |
Imperial College London
2012
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693873 |
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