Peptidomimetic approach to the inhibition of N-myristoyltransferase, a promising parasitic drug target
N-myristoyltransferase (NMT), a ubiquitous enzyme, found in a number of organisms including fungi, parasites and humans, catalyses the irreversible transfer of a C-14 chain (myristic acid) to the N-terminal glycine of specific target proteins, a process known as N-myristoylation. NMT has been report...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
Imperial College London
2012
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693873 |