Nuclear architecture and genome function in mammalian nuclei

Large-scale chromatin folding is a key mechanism in gene regulation leading to variable and dynamic gene activation in each cell. Multiple mechanisms contribute to gene regulation including the binding of regulatory factors to specific genomic sequences, chromatin interactions and repositioning of g...

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Bibliographic Details
Main Author: Lavitas, Liron-Mark
Other Authors: Pombo, Ana
Published: Imperial College London 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693863