Strategies for enhancing the therapeutic targeting of phosphatidylserine in oncological disorders and viral infections
Phosphatidylserine (PS) is exposed on a variety of tumour cell types, virus-infected cells and virions. Bavituximab, a PS-targeting antibody with a human immunoglobulin G (IgG) constant region, possesses anti-viral and anti-cancer activity that is mainly mediated by antibody-dependent cell-mediated...
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University of Oxford
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.692876 |