Biochemical, molecular and cellular studies on negative regulators of TLR-signalling
Toll-like receptors (TLRs) recognise pathogenic microorganisms through conserved pathogen associated molecular patterns, which activates the innate immune response. TLR signalling is mediated by cytoplasmic adaptor proteins via Toll/interleukin-1 receptor (TIR) domains. Sterile α- and armadillo-moti...
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Imperial College London
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.692309 |