Reprogramming the cellular response to hypoxia
HIF-1 is a heterodimeric transcription factor comprising HIF-1[alpha] and HIF-1[Beta] subunits. Cellular response to hypoxia relies on the dimerisation of HIF-1? and HIF-1? in the nucleus, forming HIF-1, which then initiates transcription of target genes. Both subunits are constitutively expressed,...
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University of Southampton
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690318 |