Directed molecular evolution of novel DNA aptamers raised against an antibiotic resistant Escherichia coli
Antimicrobial resistance presents a serious, worldwide threat to public health. New tools are required to combat the evolving problem. Here we report the systematic evolution of nucleic acid ligands to live Escherichia coli cells. Two SELEX methods were used to generate aptamers to the HB101: pAT153...
Main Author: | Gowland, Robert Michael Nicholas |
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Other Authors: | Gowers, Darren Matthew ; Scarlett, Garry ; Pickford, Andrew Robert |
Published: |
University of Portsmouth
2015
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690072 |
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