Leptin regulation of inflammatory responses in human gingival fibroblasts

Obesity and type 2 diabetes mellitus (T2DM) are positively associated with the destructive, chronic inflammatory disease periodontitis. The adipokine leptin is elevated in obesity and T2DM, and promotes inflammatory responses. Gingival fibroblasts are implicated in the pathogenesis of periodontitis...

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Bibliographic Details
Main Author: Williams, Rachel Claire
Published: University of Newcastle upon Tyne 2015
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689611