Chemical strategies for bicyclic peptide formation
The chemical constraint of proteins has been demonstrated to improve the binding affinity of peptide ligands as well as improving properties such as cell penetrability and resistance to proteases. In this work two new chemical methodologies are presented for such constraint, widening the diversity o...
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University of Leeds
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689232 |