Structural insights into the biosynthesis of spirotetronate natural products

Spirotetronates are a subclass of polyketide natural products that exhibit an array of potentially exploitable bioactivities. They are characterised by the presence of a tetronic acid ring spiro-linked to cyclohexene. A general route to their biosynthesis has been elucidated through numerous in vitr...

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Bibliographic Details
Main Author: Byrne, Matthew James
Published: University of Bristol 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687814