T cell costimulatory pathways : the role of vitamin D3
CD28-costimulatory signals interact with antigen-specific TCR signals to enhance T cell activation, proliferation and differentiation. The regulation of CD28-costimulation is controlled by CTLA-4 through its shared affinity for the CD28-ligands CD80 and CD86. CTLA-4-ig (abatacept) has emerged as an...
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University of Birmingham
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687577 |