Synthesis of selective A3 and M1 receptor agonists

Detailed within this thesis is the synthesis of three A1 agonists which were designed by Muscagen using computational studies. The agonists are derived from condensation of the modified adenosine: (4S,6R)-6-(6-chloro-9H-purin-9-yl)-N,2,2-trimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide with...

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Bibliographic Details
Main Author: Snee, Stephen
Other Authors: Thomas, Jim
Published: University of Manchester 2011
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686707