Role of the type II diabetes-associated gene SLC30A8 in the pancreatic α-cell

The SLC30A8 locus encodes the Zn2+ transporter ZnT8, whose expression is largely restricted to α- and β-cells, endocrine cells of the pancreatic islet. Genome-wide association studies have revealed > 90 loci associated with Type 2 diabetes. The first such study identified a specific single nucleo...

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Bibliographic Details
Main Author: Solomou, Antonia
Other Authors: Rutter, Guy
Published: Imperial College London 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686313