Deciphering the role of tau in hippocampal synaptic physiology

The microtubule stabilizing protein tau is enriched in axons of neuronal cells, where it plays important roles in axonal elongation and trafficking of intracellular cargo. Its propensity to aggregate and mislocalize to somatodendritic regions are considered central pathogenic effects in tauopathies...

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Bibliographic Details
Main Author: Regan, Philip
Published: University of Bristol 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685921