Extrapolating from experimental to human studies via the in vitro paradigm
Despite being the “gold standard” for toxicity testing, rat in vivo studies are estimated to be only 37-50% accurate at predicting xenobiotic toxicity in humans. If validated, in vitro systems could be incorporated into toxicity testing, allowing direct comparisons to be made between humans and rats...
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University of York
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685233 |