Impact of oligonucleotide chemistry and silencing mechanism on applications in gene silencing and genome editing
Endogenous gene regulation is an essential tool for the survival of all organisms. In recent years, scientists have gained valuable mechanistic insight into these endogenous gene regulation pathways. Using synthetic oligonucleotides (chemically modified DNA or RNA), we have been able to tap into the...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Southampton
2016
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685029 |