The roles of AMPK and LKB1 in hormone secreting cells

Regulation of insulin secretion from the pancreatic β-cell and glucagon secretion from the α-cell is vital for the control of normal glucose homeostasis. Dysfunction may lead to some forms of Diabetes. Liver kinase B1 (LKB1) is a tumour suppressor that is mutated in the premalignant disorder Peutz-J...

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Bibliographic Details
Main Author: Sayers, Sophie
Other Authors: Rutter, Guy
Published: Imperial College London 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684315