Fluorescence studies of the interactions of amyloid-β with metal ions and lipids
Amyloid-β (Aβ) metal interactions promote aggregation and produce reactive oxygen species, hallmarks of Alzheimer's disease (AD). Oligomerisation of Aβ has been proposed to be modulated by copper and zinc ions. In environments of fast molecular turnover, such as the synaptic cleft, the kinetics...
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Imperial College London
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684271 |