Structural mechanisms of gating at the selectivity filter of the human cardiac ryanodine receptor (hRyR2) channel
The cardiac ryanodine receptor (RyR2) contains structural elements within the channel pore that function as gates to regulate the release of intracellular calcium, initiating cardiac muscle contraction. The precise regulation of these gates is critical in maintaining normal cardiac function, and cha...
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Cardiff University
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683654 |